The Black Death also known as The Plague erupted on and off over the last hundreds of years claiming about 100 millions victims. Genome sequencing has revealed that the Black Death originated in China over 2000 years ago.
Black Death and The Plague - the plague is an infectious disease caused by a bacterium called Yersinia pestis. The Black Death is one huge plague event (pandemic) in history.
The Black Death is known as one of the deadliest and widespread pandemics in history. It peaked in Europe between 1348 and 1350 and is thought to have been a bubonic plague outbreak caused by Yersinia pestis, a bacterium. It reached the Crimea in 1346 and most likely spread via fleas on black rats that traveled on merchant ships. It soon spread through the Mediterranean and Europe. The Black Death is thought to have destroyed 30% to 60% of Europe's population - experts say it took 150 years for Europe to recover its population size. The plague came back several times until the 19th century, when it left Europe for good. Most victims died within two to seven days of becoming infected.
The authors in this new study say the plague evolved around the area of China over 2000 years ago and spread globally several times as deadly pandemics. They compared 17 complete plague genome sequences as well as 933 variable DNA sites on a unique worldwide collection of bacterial strains (plague isolates), allowing them to follow pandemics that took place in history around the world, and to work out the age of different waves of them.
The majority of pandemics were associated with known major historical events, such as the Black Death. As none of the collections of isolates from individual scientific institutions were globally representative, the scientists explained that in order to understand the historical sources of plagues, all the institutions would have to work together.
In order to prevent bioterrorism, access to Yersinia pestis - the bacterium known to be the cause of the plagues - is seriously restricted; therefore, assembling a comprehensive collection of them is impossible. An international team of scientists from the UK, USA, Ireland, Germany, Madagascar, China and France had to collaborate for a decentralized analysis of DNA samples.
Their findings reveal a detailed history of the pandemic spread of a bacterial disease in a way never seen before.
Pandemic infectious diseases have affected humans ever since we set foot on this planet, the authors explain. They have shaped the form of civilizations.
The researchers reveal that the plague bacillus developed near or in China, and via multiple epidemics was transmitted through several different routes, such as into West Asia through the Silk Road and Africa between 1409 and 1433 by Chinese travelers under explorer Zheng He. The Black Death made its way through Asia, Europe and Africa from 1347 to 1351, and probably brought the world's then 450 million population down to 350 million. Approximately 50% of China's population perished, while Europe's went down by a third and Africa by an eighth.
University of Cork communiqué writes:
"The last plague pandemic of 1894 spread to India and radiated to many parts of the globe, including the USA, which was infected by a single radiation still persisting today in wild rodents. Detailed analyses within the USA and Madagascar showed that subsequent country-specific evolution could be tracked by unique mutations that have accumulated in their genomes, which should prove useful to trace future disease outbreaks.".
Source - MedicalNewsToday
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